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Dysport: The Complete Patient Guide

The faster-acting Botox alternative — how Dysport works, what it costs, how it compares to other neurotoxins, and everything you need to know before your first treatment.

24-48 hr Faster onset than Botox
FDA Approved since 2009
3-4 mo Results last
$3-$5 Per unit cost

What Is Dysport?

Dysport (abobotulinumtoxinA) is an FDA-approved injectable neurotoxin manufactured by Galderma. Like Botox, it's derived from botulinum toxin type A and works by temporarily relaxing facial muscles that cause wrinkles. Dysport was first developed in the United Kingdom in the early 1990s and received FDA approval in April 2009 for the treatment of moderate to severe glabellar lines (frown lines between the eyebrows).

While Botox remains the most recognized neurotoxin brand, Dysport has become the second most popular choice among injectors and patients, with a devoted following that prefers its faster onset, broader natural spread, and often softer aesthetic result.

Key facts at a glance: Dysport uses a different formulation than Botox — it has a smaller protein complex that allows it to diffuse more broadly from the injection point. This makes it especially effective for large, flat muscle groups like the frontalis (forehead). It kicks in faster (24-48 hours vs 5-7 days for Botox), and many patients describe the result as slightly more natural and less "frozen."

How Dysport Works

Dysport works through the same fundamental mechanism as all botulinum toxin type A products:

  1. Injection: Small amounts of abobotulinumtoxinA are injected directly into specific facial muscles using a fine needle.
  2. Nerve Signal Blockade: The toxin binds to nerve endings at the neuromuscular junction, blocking the release of acetylcholine — the chemical messenger that tells muscles to contract.
  3. Muscle Relaxation: Without acetylcholine, the treated muscles can no longer contract forcefully. They relax, and the overlying skin smooths out.
  4. Wrinkle Reduction: Dynamic wrinkles (those formed by repeated muscle movement) soften or disappear entirely. Static wrinkles (those visible at rest) may also improve over time.
  5. Natural Fade: Over 3-4 months, your body naturally regenerates new nerve endings and the muscle function gradually returns, requiring retreatment.
What makes Dysport different from Botox pharmacologically: Dysport's protein complex is approximately 300-500 kDa compared to Botox's 900 kDa complex. This smaller size means Dysport diffuses more readily into surrounding tissue after injection. In practical terms: more spread per injection point, which is advantageous for large areas but requires careful technique near delicate structures like the eyelids.

Dysport vs Botox: Complete Comparison

This is the most frequently asked question about Dysport. Here's a detailed, honest comparison:

Feature Dysport Botox
Generic nameAbobotulinumtoxinAOnabotulinumtoxinA
ManufacturerGaldermaAllergan / AbbVie
FDA approved20092002 (cosmetic)
Protein complex size300-500 kDa (smaller)900 kDa (larger)
Onset of action24-48 hours5-7 days
Peak effect7-14 days10-14 days
Duration3-4 months3-6 months
Spread / diffusionBroader spreadStays more localized
Unit ratio2.5-3 units1 unit
Cost per unit$3-$5$10-$15
Cost per treatment area$150-$400$200-$500
Best for large areasYes (forehead, crow's feet)Good but needs more injection points
Best for precise areasRequires careful techniqueYes (lip flip, brow lift)
Aesthetic resultSofter, more natural movementMore precise, targeted control
Loyalty programASPIRE Galderma RewardsAlle (formerly Brilliant Distinctions)
Allergy concernContains trace cow's milk proteinContains human albumin
The bottom line on Dysport vs Botox: They're both excellent products. Dysport's advantages shine in larger treatment areas (forehead, crow's feet) where its natural spread creates smooth, even results with fewer injection points. Botox excels in precision work (lip flip, targeted brow lift, bunny lines) where you want the effect to stay exactly where you put it. Many top injectors use both products on the same patient — Dysport for the forehead and Botox for the delicate periorbital area.

Unit Conversion Guide (Dysport to Botox)

Dysport units and Botox units are NOT interchangeable. The generally accepted conversion ratio is 2.5:1 to 3:1 (Dysport : Botox). This means if your usual Botox dose is 20 units, the equivalent Dysport dose would be 50-60 units.

Dysport-to-Botox Quick Reference

50 Dysport units = 20 Botox Frown Lines
60 Dysport units = 20-24 Botox Forehead
30 Dysport units = 12 Botox Crow's Feet (per side)
120 Dysport units = ~50 Botox Full Upper Face
Why the unit difference doesn't mean Dysport is weaker: The units are simply measured differently — like comparing miles to kilometers. One mile equals 1.6 kilometers, but neither distance is "more." Similarly, 50 units of Dysport produces the same clinical effect as 20 units of Botox. The lower per-unit price of Dysport ($3-$5 vs $10-$15) reflects this conversion ratio, not a difference in potency.

Treatment Areas & Units

Dysport is FDA-approved for glabellar lines but widely used off-label across many facial areas. Here are the most common treatment areas with typical Dysport unit ranges:

Forehead Lines

Dysport units: 30-80
Botox equivalent: 10-30
Cost: $180-$400
Duration: 3-4 months
Why Dysport excels: Natural spread covers the wide frontalis muscle evenly

Frown Lines (Glabella / 11s)

Dysport units: 30-60
Botox equivalent: 10-20
Cost: $150-$350
Duration: 3-4 months
FDA approved: Yes (primary indication)

Crow's Feet

Dysport units: 24-60 per side
Botox equivalent: 8-20 per side
Cost: $125-$300 per side
Duration: 3-4 months
Note: Broader spread means fewer injection points needed

Bunny Lines (Nose)

Dysport units: 10-25
Botox equivalent: 4-10
Cost: $75-$150
Duration: 3-4 months
Note: Small area; conservative dosing recommended

Masseter / Jaw Slimming

Dysport units: 60-120 per side
Botox equivalent: 25-50 per side
Cost: $400-$800
Duration: 4-6 months
Bonus: Also treats TMJ/teeth grinding

Brow Lift

Dysport units: 5-15 per side
Botox equivalent: 2-5 per side
Cost: $75-$150
Duration: 3-4 months
Technique: Strategic placement at lateral brow tail

Lip Flip

Dysport units: 6-15
Botox equivalent: 2-6
Cost: $50-$100
Duration: 2-3 months
Caution: Precise placement critical; Botox may be preferred here

Neck Bands (Platysma)

Dysport units: 50-120
Botox equivalent: 20-50
Cost: $300-$600
Duration: 3-4 months
Also called: "Nefertiti lift"

Gummy Smile

Dysport units: 5-10
Botox equivalent: 2-4
Cost: $50-$100
Duration: 3-4 months
Target: Levator labii superioris muscle

Full Upper Face: Units Summary

Area Dysport Units Botox Equivalent Typical Cost
Forehead lines30-8010-30$180-$400
Frown lines (11s)30-6010-20$150-$350
Crow's feet (both sides)48-12016-40$250-$600
Full upper face total108-26036-90$350-$1,000

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How Long Does Dysport Last?

Dysport results typically last 3-4 months (12-16 weeks). Some patients experience results lasting up to 5 months, particularly with consistent retreatment over time. Here's a breakdown by area:

Treatment Area Typical Duration Factors
Forehead lines3-4 monthsLarge, active muscle; may wear off slightly faster
Frown lines (glabella)3-4 monthsPrimary FDA indication; consistent results
Crow's feet3-4 monthsThinner muscle; reliable duration
Masseter4-6 monthsThick muscle; higher doses last longer
Lip flip2-3 monthsHigh movement area; shortest duration
Neck bands3-4 monthsResults can vary with muscle thickness

Tips to Make Dysport Last Longer

  • Stay on schedule: Regular treatments every 3-4 months can train muscles to require less product over time.
  • Protect your skin from the sun: UV damage breaks down the effects faster and ages skin.
  • Reduce stress: High cortisol levels and facial tension can accelerate wear-off.
  • Avoid excessive exercise immediately after treatment (48 hours), though regular exercise long-term doesn't significantly affect duration.
  • Don't wait until it's completely worn off: Retreating before full movement returns (around 2.5-3 months) can extend the cumulative effect.
  • Maintain good skincare: Retinol, antioxidants, and moisturizers support overall skin health.

How Fast Does Dysport Work?

This is Dysport's biggest clinical advantage over Botox. Here's the timeline:

24-48 Hours
Initial effect visible. Most patients notice reduced muscle movement and early wrinkle smoothing within the first 1-2 days. This is significantly faster than Botox (which typically takes 5-7 days). Many patients choose Dysport specifically because of this faster onset — especially before events, vacations, or photos.
Day 3-5
Noticeable improvement. Wrinkles are visibly smoother. Muscle movement is significantly reduced. You can see a clear difference from your pre-treatment appearance.
Day 7-10
Strong results. The majority of the effect is visible. At this point, Botox patients are just beginning to see their results while Dysport patients are nearly at peak effect.
Day 14 (2 Weeks)
Full result. Maximum wrinkle reduction is achieved. This is the ideal time for a follow-up assessment. If any asymmetry or underdosing is noted, a touch-up can be performed.
Month 2-3
Results are stable and you're enjoying your smoothest skin. Some patients notice the very first signs of movement returning toward the end of month 3.
Month 3-4
Gradual return of muscle movement. Wrinkles begin reappearing. This is the typical time to schedule your next treatment (ideally before full movement returns for best cumulative results).

How Much Does Dysport Cost?

Dysport is priced per unit, and since it requires more units than Botox (2.5-3x), the per-unit price is lower. The total cost per treatment area is generally comparable to or slightly less than Botox.

Treatment Area Dysport Units Dysport Cost ($3-$5/unit) Botox Equivalent Cost
Forehead lines30-80$90-$400$100-$450
Frown lines (11s)30-60$90-$300$100-$300
Crow's feet (both)48-120$144-$600$160-$600
Full upper face108-260$324-$1,300$360-$1,350
Bunny lines10-25$30-$125$40-$150
Lip flip6-15$18-$75$20-$90
Brow lift10-30$30-$150$40-$150
Masseter (both sides)120-240$360-$1,200$500-$1,500
Neck bands50-120$150-$600$200-$750
Save money on Dysport: Galderma's ASPIRE Rewards program offers $60 savings on your first Dysport treatment and ongoing rebates of up to $60 per treatment. Combine with provider-specific package deals (many clinics offer 10-20% off when purchasing 3+ treatment sessions upfront). Some providers also offer Dysport at a lower per-unit price than Botox specifically to attract cost-conscious patients.

All 5 FDA-Approved Neurotoxins Compared

As of 2026, there are five FDA-approved botulinum toxin type A products for cosmetic use. Here's how Dysport stacks up against the competition:

Feature Dysport Botox Xeomin Jeuveau Daxxify
Generic nameAbobotulinum-toxinAOnabotulinum-toxinAIncobotulinum-toxinAPrabotulinum-toxinADaxibotulinum-toxinA
ManufacturerGaldermaAllergan/AbbVieMerzEvolusRevance
FDA approved20092002201020192022
Onset24-48 hours5-7 days3-5 days2-3 days24-48 hours
Duration3-4 months3-6 months3-4 months3-4 months6-9 months
SpreadBroadestModerateModerate-LowModerateLow-Moderate
Unit ratio to Botox2.5-3 : 11 : 11 : 11 : 10.5 : 1 (approx)
Cost per unit$3-$5$10-$15$8-$12$8-$12$12-$20
Cost per treatment$150-$400$200-$500$150-$400$150-$400$350-$650
Complexing proteinsYes (smaller)Yes (larger)None ("naked")YesYes (peptide)
Allergy concernCow's milk proteinHuman albuminNoneHuman albuminNone
Loyalty programASPIREAlleXperience+Evolus RewardsRHA Rewards
Best forLarge areas, fast results, natural lookPrecision, versatility, trusted brandSensitive patients, no protein allergiesBudget-conscious, millennial marketingLong-lasting, fewer visits
Dysport's sweet spot: Dysport is the ideal choice for patients who want fast results (24-48 hours), need treatment across large areas like the forehead, prefer a softer, more natural look with preserved facial expression, and appreciate the ASPIRE rewards program that also covers Restylane and Sculptra purchases. It's also the go-to neurotoxin for patients who have developed resistance to Botox (antibody formation).

Side Effects & Risks

Common Side Effects (Mild, Temporary)

  • Injection site pain: Brief stinging during injection, mild tenderness for hours afterward
  • Swelling: Mild swelling at injection points, resolving within 24-48 hours
  • Bruising: Occurs in 10-25% of treatments, lasting 3-7 days
  • Headache: Reported by approximately 15% of patients in clinical trials; usually mild and resolves within 24 hours
  • Redness: At injection sites, resolving within hours

Less Common Side Effects

  • Eyelid drooping (ptosis): Occurs in 1-2% of patients when product migrates to the levator muscle. Resolves in 2-4 weeks. More common with Dysport than Botox due to broader spread — an experienced injector mitigates this by proper placement and dosing.
  • Eyebrow asymmetry: One brow may drop or lift more than the other. Correctable with a small touch-up injection.
  • Heavy brow / "Spocking": Overactivity of the lateral frontalis creating peaked brows. Correctable with additional units to the lateral forehead.
  • Numbness or tingling: Temporary altered sensation near injection sites.

Rare but Serious Risks

Important safety information: In rare cases, botulinum toxin can spread beyond the injection site and cause symptoms including difficulty swallowing, breathing problems, muscle weakness, and vision changes. These are extremely rare at cosmetic doses but require immediate medical attention. Dysport should NOT be used in patients with a cow's milk protein allergy (unique to Dysport due to its manufacturing process). It is also contraindicated in patients with known hypersensitivity to botulinum toxin or any formulation component.

Aftercare Instructions

DO (First 24-48 Hours)

  • Gently exercise the treated muscles (raise eyebrows, frown, smile) for 1-2 hours post-treatment to help uptake
  • Stay upright for at least 4 hours after treatment
  • Apply a cold compress if you experience swelling
  • Resume normal gentle activities
  • Take acetaminophen (Tylenol) if needed for discomfort
  • Use sunscreen and practice sun protection

DON'T (First 24-48 Hours)

  • Rub, press, or massage the treated areas
  • Lie down flat for 4 hours after treatment
  • Exercise strenuously for 24-48 hours
  • Drink alcohol for 24 hours (increases bruising)
  • Take ibuprofen, aspirin, or blood thinners
  • Wear tight headbands, hats, or goggles that press on treated areas
  • Get facials, chemical peels, or laser treatments for 2 weeks
  • Fly on an airplane for 24 hours (not a firm rule, but some providers recommend it)

Am I a Good Candidate?

Dysport Is Ideal For

  • Patients who want faster results than Botox (event in 2-3 days? Dysport)
  • Those treating large areas like the forehead where Dysport's natural spread is an advantage
  • Patients who prefer a softer, more natural look with some preserved movement
  • Anyone who has developed resistance to Botox (antibodies to onabotulinumtoxinA)
  • Cost-conscious patients who want results comparable to Botox at potentially lower cost
  • Patients already in the ASPIRE rewards ecosystem (also covers Restylane and Sculptra)
  • Adults 18+ with moderate to severe dynamic wrinkles

Who Should NOT Get Dysport

  • Patients with cow's milk protein allergy — this is unique to Dysport and a firm contraindication
  • Pregnant or breastfeeding women
  • Patients with neuromuscular disorders (myasthenia gravis, Lambert-Eaton syndrome, ALS)
  • Those with active skin infections at the injection site
  • Patients with a known allergy to botulinum toxin of any type
  • Those taking aminoglycoside antibiotics or other drugs that interfere with neuromuscular transmission

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Frequently Asked Questions

What is Dysport?
Dysport (abobotulinumtoxinA) is an FDA-approved injectable neurotoxin made by Galderma. Like Botox, it temporarily relaxes facial muscles that cause wrinkles by blocking nerve signals. FDA-approved in 2009 for frown lines, it's widely used off-label for forehead lines, crow's feet, masseter, neck bands, and other areas. It's the second most popular neurotoxin after Botox.
What is the difference between Dysport and Botox?
Both use botulinum toxin type A but differ in formulation. Dysport has a smaller protein complex that spreads more broadly — ideal for large areas like the forehead. It works faster (24-48 hours vs 5-7 days for Botox) but may wear off slightly sooner (3-4 months vs 3-6 months). The unit ratio is 2.5-3:1 (Dysport:Botox). Dysport tends to produce a softer, more natural result; Botox offers more precise, targeted control.
How much does Dysport cost?
Dysport costs $3-$5 per unit. Treatment costs by area: forehead $180-$400 (30-80 units), frown lines $150-$350 (30-60 units), crow's feet $125-$300 per side (24-60 units), full upper face $350-$1,000. Total per-treatment cost is comparable to or slightly less than Botox. Save with Galderma's ASPIRE Rewards program ($60 off first treatment, ongoing rebates).
How long does Dysport last?
Dysport typically lasts 3-4 months (12-16 weeks). Some patients see results up to 5 months, especially with consistent retreatment. Masseter treatments last 4-6 months due to higher dosing. Lip flips last the shortest (2-3 months). Factors affecting duration include metabolism, muscle strength, treatment area, dosage, and lifestyle habits. Regular treatments can train muscles to require less product over time.
How fast does Dysport work?
Dysport begins working within 24-48 hours — significantly faster than Botox (5-7 days). Many patients notice smoothing within the first day. Full results develop over 7-14 days. This rapid onset makes Dysport popular for patients wanting quick results before events, vacations, or photos. Peak results are typically assessed at the 2-week follow-up appointment.
How many units of Dysport for forehead?
Forehead lines typically require 30-80 units of Dysport (equivalent to 10-30 Botox units). The exact amount depends on forehead size, muscle strength, wrinkle depth, and desired outcome. Frown lines (11s) need 30-60 units, crow's feet 24-60 per side. A full upper face treatment uses 108-260 total units. Your injector will customize your dosing during consultation based on your specific anatomy.
Is Dysport better than Botox?
Neither is universally better. Dysport advantages: faster onset (24-48 hours), broader spread (ideal for large areas), softer/more natural result, and sometimes lower cost. Botox advantages: more precise placement, potentially longer duration, better for small targeted areas (lip flip, brow lift), and more established brand. Many injectors use both strategically. The best product depends on your treatment goals, anatomy, and preferences.
What are the side effects of Dysport?
Common temporary side effects: injection site pain, swelling, bruising (10-25%), and headache (~15%). Less common: eyelid drooping (ptosis, 1-2%), brow asymmetry, heavy brow feeling — all resolve within 2-4 weeks. Dysport is unique in being contraindicated for patients with cow's milk protein allergy. Serious side effects (difficulty swallowing, breathing problems) are extremely rare at cosmetic doses.
What is the Dysport to Botox conversion?
The conversion ratio is 2.5:1 to 3:1 (Dysport:Botox). So 50-60 Dysport units equals approximately 20 Botox units. This exists because the products use different measurement systems — Dysport units are not interchangeable with Botox units. The lower per-unit cost of Dysport ($3-$5 vs $10-$15) reflects this ratio, making total treatment costs comparable.
Can I switch from Botox to Dysport?
Yes, you can switch freely between any neurotoxin (Botox, Dysport, Xeomin, Jeuveau, Daxxify). Wait until your current treatment has fully worn off (3-4 months) before switching. Many patients switch to Dysport for faster onset, a more natural look, or if they've developed resistance to Botox. Some practitioners also recommend switching periodically to prevent antibody formation to any single product.

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