RHA Collection is a line of resilient hyaluronic acid dermal fillers marketed in the United States by Revance and manufactured by Teoxane. The range includes RHA 2 for fine lines, RHA 3 for moderate wrinkles and folds, RHA 4 for deep folds and facial volume, and RHA Redensity for perioral lines. These products were the first fillers cleared by the FDA with specific language addressing dynamic wrinkles and folds - those that appear when the face moves.
Each RHA filler is formulated with longer hyaluronic acid chains preserved through a gentler manufacturing process. The resulting gel is intended to stretch and recoil with natural facial movement, providing a more flexible correction of dynamic lines. Like other HA fillers, RHA products can be dissolved with hyaluronidase if adjustment or removal is needed. Treatment is performed by a licensed clinician after an in-person assessment to determine the appropriate product and injection plan.
The essentials. RHA Collection is resilient hyaluronic acid (HA) dermal filler, marketed in the United States by Revance, manufactured by Teoxane and first approved by the FDA in 2020. Effect typically lasts up to about 15 months, at a typical patient price of $700 to $1,200 per syringe.
How RHA Collection Works
RHA fillers rely on hyaluronic acid, a naturally occurring substance that attracts water and adds volume beneath the skin. Because the HA chains are longer and less fragmented, the gel can deform with facial expressions and then return to its original shape, mimicking the skin's own elasticity. When injected, the filler lifts the targeted area, smooths the appearance of lines, and can restore subtle volume loss. If the result needs modification, hyaluronidase can be used to break down the HA material safely.
Products in the RHA Collection range
RHA 2 for fine lines
RHA 3 for moderate wrinkles and folds
RHA 4 for deep folds and facial volume
RHA Redensity for perioral lines
RHA Collection is administered by a licensed clinician after an in-person assessment.
Treatment Areas
Dynamic wrinkles and folds
Lines that become visible during facial movement, such as around the eyes and forehead, can be softened with RHA fillers designed for flexibility.
Nasolabial folds
The deep lines that run from the nose to the mouth corners respond well to RHA 3 or RHA 4, providing lift and smoother contour.
Perioral lines
Fine lines around the lips, often called smoker's lines, can be treated with RHA Redensity to improve texture without compromising lip movement.
Cheeks and midface
For volume loss in the cheeks or midface, RHA 4 offers a deeper filler that restores lift while moving naturally with facial expressions.
Onset and How Long It Lasts
Patients typically notice an improvement in the treated area within a few days after injection, though the filler continues to settle over the first week. The softened appearance of dynamic lines can remain visible for up to about 15 months, with the exact duration depending on the specific RHA product, the area treated, and individual factors such as metabolism, skin type, and lifestyle. Some patients may choose periodic touch-ups to maintain their desired look, but the need for additional treatment varies from person to person.
How Much Does RHA Collection Cost?
The price of an RHA filler session typically ranges from $700 to $1,200 per syringe in the United States. Total cost can vary according to the specific product selected (RHA 2, 3, 4, or Redensity), the number of syringes required to achieve the treatment goal, the clinician's experience, and regional practice pricing. Patients should discuss a personalized estimate during their consultation to understand how these factors may affect their out-of-pocket expense, and any applicable taxes.
Side Effects and Risks
Bruising at the injection site, which usually resolves within a week and may be mild.
Swelling or redness that typically subsides within a few days after treatment.
Tenderness or soreness in the treated area for several days post-procedure and mild discomfort.
Formation of small lumps or bumps that can be massaged or resolve over time.
Rare risk of vascular occlusion, which requires immediate medical attention and possible treatment with hyaluronidase.
Allergic reaction to hyaluronic acid, though uncommon, may cause itching, redness, or swelling.
Seek care urgently if you develop severe or increasing pain, skin that turns white, dusky or mottled, or any change in vision after an injection. These can be signs of a vascular complication and are treated as an emergency.
Product should be drawn and handled under sterile technique by the treating clinician.
Aftercare
Avoid touching or massaging the treated area for at least 24 hours.
Refrain from strenuous exercise, saunas, or hot tubs for 24-48 hours.
Keep your head elevated while sleeping overnight to reduce swelling.
Apply any prescribed cold compresses as directed by your clinician.
Avoid alcohol and blood-thinning supplements for 24 hours to minimize bruising.
Follow up with your injector if you notice unusual pain or prolonged swelling.
Am I a Candidate?
Ideal candidates are adults with mild to moderate dynamic wrinkles or volume loss who have realistic expectations and are in good overall health. Those seeking improvement in nasolabial folds, perioral lines, or midface volume often benefit from RHA fillers. Individuals who are pregnant, nursing, have uncontrolled bleeding disorders, or a history of severe allergic reactions to hyaluronic acid should postpone treatment until cleared by a clinician.
How RHA Collection Compares
RHA fillers differentiate themselves by being the first FDA-cleared products that specifically address dynamic wrinkles and folds, using longer hyaluronic acid chains that aim to stretch and recoil with movement. Compared with other HA fillers such as Juvederm, Restylane, or Belotero, RHA's manufacturing process is described as gentler, preserving chain length. While all provide volumizing effects and are reversible with hyaluronidase, clinicians may select RHA when flexibility for moving facial areas is a priority.
Read how Belotero compares on results, duration and cost.
Frequently Asked Questions
The RHA Collection is a series of hyaluronic acid dermal fillers made by Teoxane and sold in the U.S. by Revance. It includes RHA 2, 3, 4, and RHA Redensity, each designed for different depths of fine lines, moderate folds, deep folds, and perioral lines.
Results from RHA fillers can be visible for up to about 15 months, though the exact duration depends on the specific product used, the treated area, and individual factors such as metabolism and lifestyle. Some patients may choose periodic touch-ups to maintain their appearance.
Yes, RHA fillers are composed of hyaluronic acid, which can be broken down with an enzyme called hyaluronidase. This allows a clinician to dissolve the filler partially or completely if adjustment, removal, or an adverse reaction occurs.
RHA fillers are commonly used for dynamic wrinkles and folds, nasolabial folds, perioral lines, and to restore volume in the cheeks and midface. The specific product - RHA 2, 3, 4, or Redensity - is chosen based on the depth and location of the concern.
Typical side effects include bruising, swelling, redness, tenderness, and temporary lumps at the injection site. Rarely, vascular occlusion or an allergic reaction may occur, which would require prompt medical attention.
The number of syringes depends on the area being treated, the depth of correction desired, and the specific RHA product selected. Your injector will assess your goals during the consultation and recommend an appropriate amount.
This guide is general information, not medical advice. Whether RHA Collection suits you can only be decided by a licensed clinician who examines you in person and reviews your history and medications.
Are you a clinician who wants to offer this treatment? Hands-on workshops with live patients, physician instructors and groups of six or fewer run in cities across the United States. See upcoming dates, check tuition, or call 866-261-5164.
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